Based on its "Intelligent Design" and "Enzyme Engineering” platforms, Abiochem has developed a series of proprietary amino acid oxidases and reductases with high stereoselectivity and catalytic activity. The oxidases can specifically oxidize Glufosinate ammonium D-isomer, and the reductases can subsequently convert the oxidized intermediate of D-isomer to the L-isomer. Through the continuous enzymatic redox reaction, the content of the active ingredient of Glufosinate ammonium can be significantly increased eventually. To solve the problems such as poor enzyme stability, low dissolved oxygen concentration and unstable reaction process, Abiochem has developed an highly immobilized enzyme production technique with independent intellectual property rights, which is producible on the industrial scale, thus substantially uplifted the production efficiency of high-purity Glufosinate ammonium.
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